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By addressing appetite, fullness, insulin regulation, and food reward at the same time, CagriSema could make weight loss more sustainable, predictable, and psychologically easier for many patients

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Statistical analysis Using data generated from a pilot study and G*Power 3.1 software (Dsseldorf, Germany), it was determined that a sample size of 15 would provide 80% power to detect an increase in CNS GSH concentrations between pre- and post-administration values, with an accepted alpha value of 0.2